Organization of social adaptation of children in pre-school educational institutions takes place in the relations adult - child that have the tendency to develop transdisciplinary form of team work of teachers, specialists, parents with children. The achievement of integrity and cyclicality of the interaction adult - child in the early age takes place in the meaning space of their subject intermediaries in the subject, manipulating and playing form at the level of thinking, relations, actions and emotions. Approbation of the transdisciplinary form in pre-school educational institutions made it possible to achieve the value and targeted unity of the total adult and provide the necessary activity components for successful interaction in the process of social adaptation.